AMMAN/WASHINGTON DC — Iran fired a barrage of ballistic missiles toward a military base in Jordan used by U.S. forces on Wednesday, escalating an already widening confrontation with Washington following the destruction of five Iranian oil tankers by the United States.

Jordanian authorities said their air defenses intercepted 18 of the 20 Iranian missiles launched toward the kingdom. The remaining two missiles fell in unpopulated areas, according to Jordanian officials. A U.S. official said American military personnel in Jordan were accounted for following the attack. There were no immediate reports of U.S. casualties.

Iran said the missile attack was carried out in retaliation for recent U.S. military strikes against Iranian oil tankers. The Islamic Revolutionary Guard Corps has warned that Tehran will intensify its response to further American attacks.

The target was the Muwaffaq Salti Air Base near Al-Azraq in eastern Jordan, a strategically important facility that hosts U.S. military personnel and aircraft. The base has played a significant role in American military operations in the region.

The missile attack was part of a broader escalation on Wednesday. Iran also said it had attacked 10 vessels near the Strait of Hormuz, including oil tankers, after the United States destroyed five Iranian tankers. Washington has disputed Iranian claims that U.S. naval vessels were hit.

The latest exchange marks one of the most significant escalations in the six-month-old U.S.-Iran conflict. The confrontation has increasingly spread beyond Iran and the United States, drawing neighboring countries and international shipping into the crisis.

The Strait of Hormuz remains at the center of the escalation. The strategic waterway is one of the world’s most important routes for oil shipments, and renewed attacks on commercial vessels have raised fears of major disruptions to global energy supplies.

The developments have already shaken international energy markets. Brent crude rose sharply on Wednesday, with prices moving above the $100-a-barrel level amid fears that the fighting could disrupt oil production and shipping in the Gulf.

The United States has said its military operations against Iranian vessels were carried out in response to attacks by Iran’s Revolutionary Guard on an American warship. Iran, meanwhile, has threatened further retaliation and warned that the area of restricted maritime activity around the Strait of Hormuz could be expanded.

The latest missile attack on Jordan raises concerns that the conflict could increasingly involve U.S. military facilities and American allies across the Middle East, increasing the risk of a broader regional war.

With Iran threatening further retaliation and the United States continuing military operations against Iranian targets, governments across the region are closely monitoring the situation for signs of another major escalation.

TEHRAN — Iran’s Islamic Revolutionary Guard Corps said Wednesday that it launched a missile attack against a U.S.-linked military base in Jordan, escalating tensions after American forces destroyed five Iranian oil tankers. The latest exchange marks another sharp escalation in the six-month-old U.S.-Iran war, with the conflict increasingly threatening regional security and global energy supplies.

Iran said its missile strike targeted the Al-Azraq air base in Jordan, which hosts U.S. military assets. Iranian state media reported that the operation damaged maintenance and repair facilities, aircraft deployment areas and shelters. Those damage claims could not immediately be independently verified. Jordan’s military said it intercepted 18 ballistic missiles launched from Iran toward the kingdom. No casualties were immediately reported.

The Iranian attack came after U.S. forces destroyed five Iranian oil tankers on Tuesday. The U.S. military said the crews were ordered to abandon the vessels before they were struck. The operation followed an Iranian attack targeting a U.S. Navy warship. Iranian officials had previously warned that American military bases in the region would be targeted if Washington attacked Iranian oil tankers.

Iran has also threatened to target oil tankers operating near U.S.-allied Kuwait and Bahrain. The threats have heightened fears of further disruption to commercial shipping across the Persian Gulf and the Strait of Hormuz.

The strategic waterway has become a major flashpoint in the conflict. Shipping through the Strait of Hormuz has fallen sharply, raising concerns about global oil and gas supplies. Reuters reported Wednesday that only six commodity vessels transited the strait on Tuesday, well below the recent average.

The escalation has also pushed oil prices higher. Brent crude approached $100 a barrel on Wednesday, while U.S. West Texas Intermediate crude traded above $94 a barrel as markets assessed the risk of further supply disruptions.

U.S. Secretary of State Marco Rubio has warned that Washington will continue responding to Iranian attacks. The latest U.S. strikes on Iranian tankers were described by American officials as retaliation for attacks on U.S. naval forces.

Iranian state media also claimed that the Revolutionary Guard had attacked two U.S. destroyers with ballistic missiles. The claim had not been independently confirmed by the U.S. military and should be treated as an Iranian claim.

The latest confrontation comes as both sides remain locked in a wider struggle over control of the Strait of Hormuz, a vital route for global energy shipments. With Iran threatening further attacks on shipping and U.S. forces continuing operations against Iranian assets, concerns are growing that the conflict could expand further across the Middle East and place additional pressure on global energy markets.